The National Multiple Sclerosis Society (NMSS) is an organization with a network of chapters throughout the US. The organization's goal is to move towards a world free of multiple sclerosis, a debilitating disease that attacks the central nervous system. Over time, those suffering from MS become less able to move and function on their own, which is why the Society seeks to fund research and develop medications to both treat and cure MS.

Upcoming 2010 MS rides include:
- Atlanta to Athens, April 10-11
Atlanta, GA
- BP MS150, April 17-18
Houston, TX
- Zimmerman MS Bike Ride Presented by Mack Cycle and Fitness, April 17-18
Homestead, FL
- Ride the Vineyard, May 01
Martha's Vineyard, MA
- SAM'S Club Ride, May 01 - 02
Frisco, TX
- Allianz Twin Cities Ride, May 08
Maplewood, MN
- The Citrus Tour, May 15 - 16
Lake Wales, FL
- Chesapeake Challenge, May 22 - 23
Chestertown, MD
- Coast the Coast Ride, May 22 - 23
West Long Branch, NJ
- Ride Virginia, May 22 - 23 Richmond, VA